ICRP Publication 148

Radiation Weighting for Reference Animals and Plants

Recommended citation
ICRP, 2021. Radiation weighting for Reference Animals and Plants. ICRP Publication 148. Ann. ICRP 50(2).

Authors on behalf of ICRP
K. Higley, A. Real, D. Chambers

Abstract - It has long been recognised that the degree of biological impact on an organism resulting from a given absorbed dose (in gray, Gy) of ionising radiation can vary depending upon the type of radiation involved. This difference has been experimentally quantified and reported as relative biological effectiveness (RBE) of specific radiation types. RBE values are determined experimentally and are the ratio of doses of a test radiation and a low-linear energy transfer (LET) reference radiation that produce the same level of observed effect. RBE values have been measured for a variety of endpoints in in-vitro experiments that include human and animal cell lines, as well as in in-vivo experiments with animals. Such studies have shown that the magnitude of a biological effect depends not only on the dose and the type and energy of the radiation delivering the dose, but also on the rate at which the dose is delivered and, most importantly, the endpoint under study. The need to apply this knowledge to radiological protection of humans has led to an aggregation and analysis of RBE data to provide radiation weighting factors, and to the radiation protection quantity equivalent dose (in sievert, Sv) where the absorbed dose is multiplied by the radiation weighting factor appropriate for the type of radiation considered. Whereas protection of humans has focused on avoiding tissue reactions (deterministic) and limiting stochastic (cancer/heritable) effects, protection of biota has largely focused on endpoints relevant to population viability. This publication reviews RBE data relevant to biota for one low-energy beta emitter (tritium) and for alpha-emitting radionuclides. For tritium, reported values centred around 1.52 compared with x rays and 22.5 compared with gamma rays; values for alpha particles were generally substantially higher. It is proposed that an RBE weighted absorbed dose should be used for protection purposes, with an RBE weighting for biota of 1 for all low-LET radiations and 10 for alpha particles. Use of a single value of 1 for all low-LET radiations is consistent with the approach taken to protection of humans. However, if exposures to tritium beta particles or other low-energy, lowLET radiations are estimated to be within or close to the derived consideration reference level, the use of higher RBE values may be warranted.