ICRP Publication 133
The ICRP Computational Framework for Internal Dose Assessment for Reference Adults: Specific Absorbed Fractions
Recommended citation
ICRP, 2016. The ICRP computational framework for internal dose assessment for reference adults: specific absorbed fractions. ICRP Publication 133. Ann. ICRP 45(2), 1–74.
Authors on behalf of ICRP
W.E. Bolch, D. Jokisch, M. Zankl, K.F. Eckerman, T. Fell, R. Manger, A. Endo, J. Hunt, K.P. Kim, N. Petoussi-Henss
Abstract - Dose coefficients for assessment of internal exposures to radionuclides are radiological protection quantities giving either the organ equivalent dose or effective dose per intake of radionuclide following ingestion or inhalation. In the International Commission on Radiological Protection’s (ICRP) Occupational Intakes of Radionuclides (OIR) publication series, new biokinetic models for distribution of internalised radionuclides in the human body are presented as needed for establishing time-integrated activity within organs of deposition (source regions). This series of publications replaces Publications 30 and 68 (ICRP, 1979, 1980, 1981, 1988, 1994b). In addition, other fundamental data needed for computation of the dose coefficients are radionuclide decay data (energies and yields of emitted radiations), which are given in Publication 107 (ICRP, 2008), and specific absorbed fraction (SAF) values – defined as the fraction of the particle energy emitted in a source tissue region that is deposited in a target tissue region per mass of target tissue. This publication provides the technical basis for SAFs relevant to internalised radionuclide activity in the organs of Reference Adult Male and Reference Adult Female as defined in Publications 89 and 110 (ICRP, 2002, 2009). SAFs are given for uniform distributions of mono-energetic photons, electrons, alpha particles, and fission-spectrum neutrons over a range of relevant energies. Electron SAFs include both collision and radiative components of energy deposition. SAF data are matched to source and target organs of the biokinetic models of the OIR publication series, as well as the Publication 100 (ICRP, 2006) Human Alimentary Tract Model and the Publication 66 (ICRP, 1994a) Human Respiratory Tract Model, the latter as revised within Publication 130 (ICRP, 2015). This publica- tion further outlines the computational methodology and nomenclature for assess- ment of internal dose in a manner consistent with that used for nuclear medicine applications. Numerical data for particle-specific and energy-dependent SAFs are given in electronic format for numerical coupling to the respiratory tract, alimentary tract, and systemic biokinetic models of the OIR publication series.
© 2016 ICRP. Published by SAGE.
Keywords: Computational phantom; Absorbed fraction; Specific absorbed fraction; Radiation transport; Internal dosimetry.
AUTHORS ON BEHALF OF ICRP W.E. BOLCH, D. JOKISCH, M. ZANKL, K.F. ECKERMAN, T. FELL, R. MANGER, A. ENDO, J. HUNT, K.P. KIM, N. PETOUSSI-HENSS
Key Points
Dose coefficients for assessment of internal exposure to radionuclides following inhalation and ingestion require the use of biokinetic models [Publication 130 (ICRP, 2015)], radionuclide decay scheme data [Publication 107 (ICRP, 2008)], and specific absorbed fraction (SAF) values in a computational phantom.
SAFs are defined as the fraction of particle energy emitted in a source region that is deposited in a target region per mass of target tissue, and are expressed in units of kg-1.
This publication presents reference values of the SAFs for internally emitted photons, electrons, and alpha particles, as well as fission-spectrum neutrons associated with radionuclides that decay by spontaneous fission.
The majority of SAF values given in this publication are derived from Monte Carlo radiation transport simulations in Reference Adult Male and Reference Adult Female computational phantoms defined in Publication 110 (ICRP, 2009).
Additional SAF values for electron and alpha particles are taken from Publication 66 (ICRP, 1994a) for the Human Respiratory Tract Model (HRTM), with changes consistent with revisions to the HRTM presented in Publication 130 (ICRP, 2015).
In this publication, new SAF values for electron and alpha particles are given for the Human Alimentary Tract Model (HATM) that supercede those given in Publication 100 (ICRP, 2006).
The reference SAFs presented in this publication are numerically coupled to the compartmental models of the HRTM, HATM, and the systemic biokinetic models of Publication 130 (ICRP, 2015) in the calculation of reference dose coefficients for both tissue-specific equivalent dose and effective dose.
Executive Summary: Not included in this publication
ICRP, 2016. The ICRP computational framework for internal dose assessment for reference adults: specific absorbed fractions. ICRP Publication 133. Ann. ICRP 45(2), 1–74.
Authors on behalf of ICRP
W.E. Bolch, D. Jokisch, M. Zankl, K.F. Eckerman, T. Fell, R. Manger, A. Endo, J. Hunt, K.P. Kim, N. Petoussi-Henss
Abstract - Dose coefficients for assessment of internal exposures to radionuclides are radiological protection quantities giving either the organ equivalent dose or effective dose per intake of radionuclide following ingestion or inhalation. In the International Commission on Radiological Protection’s (ICRP) Occupational Intakes of Radionuclides (OIR) publication series, new biokinetic models for distribution of internalised radionuclides in the human body are presented as needed for establishing time-integrated activity within organs of deposition (source regions). This series of publications replaces Publications 30 and 68 (ICRP, 1979, 1980, 1981, 1988, 1994b). In addition, other fundamental data needed for computation of the dose coefficients are radionuclide decay data (energies and yields of emitted radiations), which are given in Publication 107 (ICRP, 2008), and specific absorbed fraction (SAF) values – defined as the fraction of the particle energy emitted in a source tissue region that is deposited in a target tissue region per mass of target tissue. This publication provides the technical basis for SAFs relevant to internalised radionuclide activity in the organs of Reference Adult Male and Reference Adult Female as defined in Publications 89 and 110 (ICRP, 2002, 2009). SAFs are given for uniform distributions of mono-energetic photons, electrons, alpha particles, and fission-spectrum neutrons over a range of relevant energies. Electron SAFs include both collision and radiative components of energy deposition. SAF data are matched to source and target organs of the biokinetic models of the OIR publication series, as well as the Publication 100 (ICRP, 2006) Human Alimentary Tract Model and the Publication 66 (ICRP, 1994a) Human Respiratory Tract Model, the latter as revised within Publication 130 (ICRP, 2015). This publica- tion further outlines the computational methodology and nomenclature for assess- ment of internal dose in a manner consistent with that used for nuclear medicine applications. Numerical data for particle-specific and energy-dependent SAFs are given in electronic format for numerical coupling to the respiratory tract, alimentary tract, and systemic biokinetic models of the OIR publication series.
© 2016 ICRP. Published by SAGE.
Keywords: Computational phantom; Absorbed fraction; Specific absorbed fraction; Radiation transport; Internal dosimetry.
AUTHORS ON BEHALF OF ICRP W.E. BOLCH, D. JOKISCH, M. ZANKL, K.F. ECKERMAN, T. FELL, R. MANGER, A. ENDO, J. HUNT, K.P. KIM, N. PETOUSSI-HENSS
Key Points
Dose coefficients for assessment of internal exposure to radionuclides following inhalation and ingestion require the use of biokinetic models [Publication 130 (ICRP, 2015)], radionuclide decay scheme data [Publication 107 (ICRP, 2008)], and specific absorbed fraction (SAF) values in a computational phantom.
SAFs are defined as the fraction of particle energy emitted in a source region that is deposited in a target region per mass of target tissue, and are expressed in units of kg-1.
This publication presents reference values of the SAFs for internally emitted photons, electrons, and alpha particles, as well as fission-spectrum neutrons associated with radionuclides that decay by spontaneous fission.
The majority of SAF values given in this publication are derived from Monte Carlo radiation transport simulations in Reference Adult Male and Reference Adult Female computational phantoms defined in Publication 110 (ICRP, 2009).
Additional SAF values for electron and alpha particles are taken from Publication 66 (ICRP, 1994a) for the Human Respiratory Tract Model (HRTM), with changes consistent with revisions to the HRTM presented in Publication 130 (ICRP, 2015).
In this publication, new SAF values for electron and alpha particles are given for the Human Alimentary Tract Model (HATM) that supercede those given in Publication 100 (ICRP, 2006).
The reference SAFs presented in this publication are numerically coupled to the compartmental models of the HRTM, HATM, and the systemic biokinetic models of Publication 130 (ICRP, 2015) in the calculation of reference dose coefficients for both tissue-specific equivalent dose and effective dose.
Executive Summary: Not included in this publication
